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Gastric decontamination with activated charcoal ought to be administered just just before N-acetylcysteine (NAC) to lessen systemic absorption if Acetaminophen ingestion is understood or suspected to acquire transpired in just a handful of hours of presentation.
If concomitant use with CYP2D6 inhibitors is necessary, follow the patient for diminished efficacy or signs and symptoms of opioid withdrawal and consider escalating the Acetaminophen, Caffeine, and Dihydrocodeine Bitartrate as needed.
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Prijavljivanjem neželjenih reakcija možete da pomognete u proceni bezbednosti ovog leka. Sumnju na neželjene reakcije možete da prijavite Agenciji za lekove i medicinska sredstva Srbije (ALIMS):
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For respiratory despair as a result of uncommon sensitivity to dihydrocodeine, parenteral naloxone is a particular and successful antagonist.
People working experience anterograde amnesia following drug administration if plasma concentrations are significant in the course of the stimulus. This really is attributed to both inattention or consolidation of the memory method.[25]
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Suggest both equally clients and caregivers with regard to the threats of respiratory despair and sedation when Acetaminophen, Caffeine, and Dihydrocodeine Bitartrate is utilised with benzodiazepines or other CNS depressants (such as Alcoholic beverages and illicit medicine). Suggest patients not to travel or run hefty machinery till the results of concomitant use with the benzodiazepine or other CNS depressant happen to be decided.